Stephen D Ginsberg Selected Research

Cholinergic Agents (Cholinergics)

1/2019	Maternal Choline Supplementation Alters Basal Forebrain Cholinergic Neuron Gene Expression in the Ts65Dn Mouse Model of Down Syndrome.
1/2018	Pretangle pathology within cholinergic nucleus basalis neurons coincides with neurotrophic and neurotransmitter receptor gene dysregulation during the progression of Alzheimer's disease.
1/2018	CA1 pyramidal neuron gene expression mosaics in the Ts65Dn murine model of Down syndrome and Alzheimer's disease following maternal choline supplementation.
3/2016	Partial BACE1 reduction in a Down syndrome mouse model blocks Alzheimer-related endosomal anomalies and cholinergic neurodegeneration: role of APP-CTF.
1/2016	Effects of Maternal Choline Supplementation on the Septohippocampal Cholinergic System in the Ts65Dn Mouse Model of Down Syndrome.
9/2015	Expression profile analysis of hippocampal CA1 pyramidal neurons in aged Ts65Dn mice, a model of Down syndrome (DS) and Alzheimer's disease (AD).
1/2015	Expression profile analysis of vulnerable CA1 pyramidal neurons in young-Middle-Aged Ts65Dn mice.
1/2014	Sex differences in the cholinergic basal forebrain in the Ts65Dn mouse model of Down syndrome and Alzheimer's disease.
2/2012	Rac1b increases with progressive tau pathology within cholinergic nucleus basalis neurons in Alzheimer's disease.
10/2011	Gender differences in neurotrophin and glutamate receptor expression in cholinergic nucleus basalis neurons during the progression of Alzheimer's disease.

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Stephen D Ginsberg Research Topics

Disease

54	Alzheimer Disease (Alzheimer's Disease) 01/2022 - 10/2002
23	Cognitive Dysfunction 01/2022 - 10/2004
19	Down Syndrome (Down's Syndrome) 07/2021 - 07/2009
5	Dementia (Dementias) 01/2022 - 10/2011
5	Neurodegenerative Diseases (Neurodegenerative Disease) 12/2021 - 01/2009
4	Disease Progression 10/2021 - 07/2006
4	Amyloidosis 03/2016 - 02/2009
3	Neoplasms (Cancer) 11/2021 - 01/2020
3	Schizophrenia (Dementia Praecox) 06/2020 - 07/2002
3	Intellectual Disability (Idiocy) 01/2018 - 09/2015
2	Amyloid Plaque 12/2019 - 01/2016
2	Trisomy (Trisomies) 01/2019 - 01/2016
2	Diabetes Mellitus 04/2016 - 01/2012
2	Bipolar Disorder (Manic Depressive Psychosis) 02/2012 - 01/2009
1	Pancreatic Neoplasms (Pancreatic Cancer) 11/2021
1	Neuroinflammatory Diseases 01/2020
1	Virus Diseases (Viral Diseases) 01/2020
1	AIDS-Related Complex (ARC) 01/2019
1	Neurodevelopmental Disorders 01/2019
1	HIV Infections (HIV Infection) 01/2018
1	Classical Lissencephalies and Subcortical Band Heterotopias 01/2018
1	Neuroblastoma 12/2016
1	Glucocorticoid Receptor Deficiency 11/2016
1	Atrophy 11/2016
1	Insulin Resistance 04/2016
1	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 04/2016
1	Neuronal Ceroid-Lipofuscinoses (Neuronal Ceroid Lipofuscinosis) 04/2016
1	Body Weight (Weight, Body) 01/2012
1	Autistic Disorder (Autism) 04/2011
1	Hyponatremia 02/2011
1	Progressive Myoclonic Epilepsies (Progressive Myoclonic Epilepsy) 11/2010
1	Memory Disorders (Memory Loss) 07/2009

Drug/Important Bio-Agent (IBA)

25	Cholinergic Agents (Cholinergics)IBA 01/2019 - 10/2002
16	Proteins (Proteins, Gene)FDA Link 11/2021 - 07/2002
12	Amyloid (Amyloid Fibrils)IBA 11/2020 - 02/2009
11	Choline (Choline Chloride)IBA 07/2021 - 10/2013
8	Nerve Growth Factors (Neurotrophins)IBA 01/2022 - 09/2007
7	Brain-Derived Neurotrophic Factor (BDNF)IBA 01/2022 - 01/2009
6	Amyloid beta-PeptidesIBA 03/2016 - 02/2009
6	Messenger RNA (mRNA)IBA 09/2009 - 07/2002
5	RNA (Ribonucleic Acid)IBA 01/2022 - 07/2006
5	Nerve Growth Factor (NGF)IBA 01/2019 - 09/2007
5	GalaninIBA 01/2010 - 05/2003
4	EnzymesIBA 01/2018 - 05/2009
3	Insulin (Novolin)FDA Link 04/2016 - 01/2009
3	Peptides (Polypeptides)IBA 01/2016 - 05/2009
2	ApolipoproteinsIBA 01/2022 - 01/2019
2	Biomarkers (Surrogate Marker)IBA 06/2020 - 01/2016
2	Nerve Growth Factor Receptors (Neurotrophin Receptors)IBA 12/2019 - 01/2019
2	Neurotransmitter Agents (Neurotransmitter)IBA 01/2018 - 01/2009
2	Glutamate Receptors (Glutamate Receptor)IBA 02/2012 - 10/2011
2	rab GTP-Binding ProteinsIBA 10/2011 - 01/2010
2	Adenosine Triphosphate (ATP)IBA 04/2011 - 01/2009
2	Pharmaceutical PreparationsIBA 01/2009 - 11/2008
2	Choline O-Acetyltransferase (Choline Acetyltransferase)IBA 11/2008 - 01/2008
1	Hydrocortisone (Cortisol)FDA LinkGeneric 01/2022
1	Complement System Proteins (Complement)IBA 01/2022
1	Glucocorticoid Receptors (Glucocorticoid Receptor)IBA 01/2022
1	Apolipoproteins E (ApoE)IBA 01/2022
1	Apolipoprotein E4IBA 01/2022
1	AdiponectinIBA 07/2021
1	ProteomeIBA 01/2021
1	Cathepsin DIBA 11/2020
1	Interferon Type IIBA 01/2020
1	CytokinesIBA 01/2020
1	GTP-Binding Proteins (G-Protein)IBA 01/2019
1	Chloride Channels (Chloride Channel)IBA 01/2018
1	adenylate cyclase 3IBA 01/2018
1	Catechol O-Methyltransferase (Methyltransferase, Catechol)IBA 01/2018
1	Dopa DecarboxylaseIBA 01/2018
1	ElementsIBA 01/2018
1	Cholinergic ReceptorsIBA 01/2018
1	Neurotransmitter Receptors (Neurotransmitter Receptor)IBA 01/2018
1	Caveolin 1IBA 01/2018
1	Tyrosine 3-Monooxygenase (Tyrosine Hydroxylase)IBA 01/2017
1	Dual Specificity Phosphatase 1IBA 11/2016
1	GlucocorticoidsIBA 11/2016
1	Insulin Receptor Substrate ProteinsIBA 04/2016
1	Neprilysin (Neutral Endopeptidase)IBA 04/2016
1	Streptozocin (Streptozotocin)FDA Link 04/2016
1	AcetylcholinesteraseIBA 01/2016
1	tau Proteins (tau Protein)IBA 01/2016
1	Reticulin (Reticular Fiber)IBA 02/2011
1	Mercuric Chloride (Sublimate)IBA 02/2011
1	ElectrolytesIBA 02/2011
1	Cystatin CIBA 11/2010
1	Cystatin BIBA 11/2010
1	AntibodiesIBA 01/2010
1	ImmunosorbentsIBA 05/2009
1	methyllycaconitineIBA 05/2009
1	alpha7 Nicotinic Acetylcholine ReceptorIBA 05/2009
1	trkB ReceptorIBA 01/2009
1	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2009
1	Glutamate Decarboxylase (Decarboxylase, Glutamate)IBA 01/2009
1	Glutamic Acid (Glutamate)FDA Link 01/2009
1	gamma-Aminobutyric Acid (GABA)IBA 01/2009

Therapy/Procedure

4	Therapeutics 11/2021 - 01/2016
3	Lasers (Laser) 11/2020 - 01/2012
1	Precision Medicine 12/2021
1	Injections 04/2016